Prevalence and Disposition of Drugs of Abuse and Opioid Treatment Drugs in Oral Fluid

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Oral fluid testing for drugs of abuse.

BACKGROUND Oral fluid (OF) is an exciting alternative matrix for monitoring drugs of abuse in workplace, clinical toxicology, criminal justice, and driving under the influence of drugs (DUID) programs. During the last 5 years, scientific and technological advances in OF collection, point-of-collection testing devices, and screening and confirmation methods were achieved. Guidelines were propose...

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Interpretation of oral fluid tests for drugs of abuse.

Oral fluid testing for drugs of abuse offers significant advantages over urine as a test matrix. Collection can be performed under direct observation with reduced risk of adulteration and substitution. Drugs generally appear in oral fluid by passive diffusion from blood, but also may be deposited in the oral cavity during oral, smoked, and intranasal administration. Drug metabolites also can be...

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ژورنال

عنوان ژورنال: Journal of Analytical Toxicology

سال: 2007

ISSN: 0146-4760,1945-2403

DOI: 10.1093/jat/31.8.424